The high molecular weight hyaluronic acid acts as a protective macromolecule for the vaginal mucosa and also favors the penetration of the low molecular weight molecule into the deeper vaginal layers.
The physicochemical properties of high molecular weight HA contribute to passive structural effects, demonstrating hygroscopicity and viscoelasticity and improving hydration, water balance, and structural integrity. Hyaluronic acid anionic properties cause it to attract water and induce swelling, increasing tissue volume and structural integrity of the skin
Hyaluronic acid is the main component of the derma’s fundamental substance, and it is widely used in dermatology because:
- Form extracellular water film;
- Maintain the extracellular swelling;
- Moisturize the skin.
Hyaluronic acid is contained in the Halova medical device in the amount of 5mg/ovule, with the role to hydrate the atrophic vaginal mucosa, especially in women for whom hormonal treatment is not indicated. The action mechanism of hyaluronic acid is a mechanical one, not involving pharmacological, immunological or metabolic processes.